Cold Spring Harbor Laboratory
Dr. Richard McCombie
Prior to his Steamboat summer, Nathan Huey studied at Kenyon College in rural Gambier, OH. Nathan is majoring in mathematics, but also works in the molecular biology laboratory of Dr. Wade Powell where he studies the changes in gene expression mediated by the aryl hydrocarbon receptor in the African clawed frog. His dual interests in mathematics and biology led him to the burgeoning field of bioinformatics, the collection and analysis of the sequences of key biological molecules. In his prior summers he has gained experience on both sides of the bench : data collection and the subsequent analysis, allowing him to receive a Goldwater scholarship his sophomore year at Kenyon. The cutting-edge bioinformatics research at Cold Spring Harbor was the ideal venue to continue his exploration of the field and gain valuable exposure to a dedicated scientific community.
Nathan spent his summer in the lab of Dr. Richard McCombie at the Woodbury Genome Center of Cold Spring Harbor Laboratory where he studied how DNA sequencing technology can be used to identify the genetic basis of complex psychiatric diseases. Here, he was able to study the application of bioinformatics from the sequencing process itself in the lab to the processing of raw sequence data and finally to analysis and interpretation. The resources at CSHL enabled him to immerse himself in the scientific process through his own research identifying areas of rare mutations in a network of interacting genes known as the "DISC1 Interactome", by attending lectures by leading experts in the field of bioinformatics and from conversations with others in the URP program.
Nathan is currently finishing his senior year at Kenyon College.
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